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Triglicor with Niacin

Other Ingredients: Gelatin, Natural Mixed Tocopherols 90%, Vegetable Stearine, Vegetable Cellulose, Carnauba Wax, Magnesium Stearate (Vegetable), Silica, Natural Vegetable Capsules, Glycerin, Purified Marine Triglyceride Concentrate and Purified Water. NiamaxTM is a trademark of Lonza Ltd.

SUGGESTED USE: 2 packets per day with a meal or as recommended by your health care professional.

Formulated to be free of allergens derived from: Gluten, yeast, artificial colors and flavors. Contains soy. If you are pregnant or nursing, consult your physician before taking this product. As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used. Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.This product is designed to release Niacin over a 6-8 hour period to minimize flushing (Avoiding hot beverages is recommended). A small percentage of people may still experience harmless flushing while taking this product.

Contraindications, Adverse or other Reactions: Do not consume this product if you are pregnant or nursing. Consult your physician for further information. This product contains the following potential allergen: Fish. This product is designed to release niacin over a 6-8 hour period to minimize the amount of flushing. A small percentage of people may still experience harmless flushing while taking this product.

“Products containing at least 0.65 g per serving of plant sterol esters, taken twice daily with meals for a daily total intake of at least 1.3 g, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease.”

“Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease. One serving of Triglicor with Niacin provides 1.44 grams of EPA and DHA omega-3 fatty acids.”

DISCLAIMER: The information contained on this web site has not been evaluated by the FDA. It is not intended to treat, diagnose, cure or prevent any disease. Material on the Imupharm web site is provided for educational purposes only. Always seek the advice of your physician or other qualified health care provider with any questions you have regarding a medical condition, and before undertaking any diet, exercise or other health program.



Omega-3 Fish Oils

The current American diet is laden with an overabundance of omega-6 fatty acids, whereas omega-3 fatty acids from fish are vital for the maintenance of fatty acid homeostasis and are the most potent immunomodulatory agents among the fatty acids. (Reference 1)

Long suspected as an aid in cardiovascular health, omega-3 fatty acids are being validated through worldwide research to confirm their efficacy. (Reference 2)

Our unique oils have no fishy taste and are burp-free for nearly everyone. Our omega-3 fish oils also meet the strictest international trade criteria for trace heavy metals such as mercury, as well as pesticide concentrations such as PCBs and dioxins.

Plant Sterols

Plant sterols, also called phytosterols and stanols, are substances found in many medicinal plants such as milk thistle, saw palmetto, ginseng, and others. They are present in small quantities in many fruits, vegetables, vegetable oils, nuts, seeds, cereals and legumes.

Sterols have been shown to restore immune balance in various forms of immune suppression. (Reference 3) Different sterols influence the immune system differently.

They have been shown in every study to enhance immune function. For example, if the body responds to a viral challenge with too much T-helper2 cell activity, sterols can correct this imbalance. They help the T-helper1 cells produce more interferon to fight colds (and other viruses such as HIV and hepatitis C) which helps turn off the allergy-promoting T-helper2 cells. (Reference 4)

A study conducted at the University of Buffalo, New York released on April 29, 1999 stated that plant sterols reduce the number of breast cancer cells grown in a laboratory by 66%, compared to controls. The leading researcher Atif Awad, Ph.D. from the University of Buffalo presented these findings at the annual meeting of the Federation of American Societies of Experimental Biology.

Foods containing at least 0.65 g per serving of plant sterol esters, taken twice daily with meals for a daily total intake of at least 1.3 g, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. The National Cholesterol Education Program (NCEP) of the National Heart, Lung and Blood Institute of Health suggests the use of plant sterols in conjunction with other lifestyle changes to support LDL cholesterol reduction.

Numerous clinical trials have been performed with phytosterols and they have proven to be both safe and effective in a wide group of individuals. Two packets of Triglicor contain 1.3 g of plant sterol esters.

Pantethine

Pantothenic acid, better known as Vitamin B5, is a form of vitamin manufactured by plants. In the body, pantothenic acid is converted to pantethine. Pantethine supplements (but not pantothenic acid supplements) appear to reduce blood levels of triglycerides and also improve the cholesterol profile.

Two mechanisms of action are proposed for pantethine (Reference 5)

  •  In the first, pantethine serves as the precursor for synthesis of coenzyme A, which is the most active metabolic enzyme in the human body and important for immune health. In the second, pantethine is converted to two pantetheine molecules which are in turn metabolized to form two pantothenic acid and two cysteamine molecules. Cysteamine is theorized to bind to and thus inactivate sulfur-containing amino acids in liver enzymes involved in the production of cholesterol and triglycerides.

  •  Pantethine has shown to support normal platelet function, endothelial responsiveness, and has overall antioxidant and immune benefits. Much additional research is pending which is likely to show pantethine to be a leading natural supporter of cardiovascular health. Two packets of Triglicor provide 900 mg of pantethine, the recommended daily dose in clinical studies.

Time-Release Niacin

Niacin, also known as nicotinic acid or vitamin B 3, is an essential vitamin that supports energy metabolism and reactions involving mitochondrial electron transport and numerous enzyme reactions. Studies found that Niacin may be a protective factor that limits carcinogenic events. (References 6, 7)

First researched over 40 years ago, niacin, continues to be one of the most studied, and most recommended, ingredients of supplements for lipid balance and herewith cardiovascular health. Niacin is considered a first-line approach by nearly every panel, including NCEP (The National Cholesterol Education Panel), for maintaining blood lipid levels that are already in the normal range. The use of niacin is often limited by the bothersome side-effect of flushing in many of the patients taking high doses of instant release niacin. Our time-released form of niacin not only maintains normal-range lipid levels as seen with instant release forms, it dramatically reduces the flushing effect allowing more people to realize the benefits of niacin. Our wax-coated technology permits a release that is complete in 6-8 hours, considered ideal for time-released niacin.

Support for:
  •  Overall Immune Health and Cardiovascular Health

Imupharm Difference for Cardiovascular Health:
  •  Triglicor combines four of the most powerful ingredients in a single-serving packet, making compliance easy and efficacy unmatched.
  •  We chose four of the most studied ingredients for Triglicor— all with stellar performance and a long history of success.
  •  Each of the four primary ingredients work through distinct pathways, ensuring the full benefit of each to the body.
  •  Imupharm’s time-release niacin utilizes a wax-coated technology that permits a complete release within 6-8 hours.
  •  Imupharm’s time-release niacin dramatically reduces the flushing effect that is common
with niacin products.



(1) Kehn P, Fernandes G: The importance of omega-3 fatty acids in the attenuation of immuno-mediated diseases.J Clin Immunol21 :99 –101,2001. [Medline]

(2) American Heart Association. Home page. Fish and Omega-3 Fatty Acids. [http://www.americanheart.org]

(3) Alternative Medicine Review, 2001, vol. 6, no. 2

(4) The Lancet 1989 (#8644 pg 943).

(5) McCarty MF. Medical Hypotheses 2001;56(3):314-317.

(6) Jacboson EL. Niacin deficiency and cancer in women. J AM Coll Nutr 1993;12(4):412-416 PubMed.

(7) Gensler HL, William T, Huang AC, Jacobson EL. Oral niacin prevents photocarcinogenesis and photoimmunosuppression in mice. Nutr Cancer 1999:34(1):36-41 PubMed.