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Adrenal Formula

Other Ingredients: Natural Vegetable Capsules. This product may contain one or more of the following: Calcium Silicate, Magnesium Stearate, Microcrystalline Cellulose and Silicon Dioxide. Betatene® is a registered trademark of Cognis B.V.

SUGGESTED USE: 2 capsules 1-2 times per day on an empty stomach or as recommended by your health care professional.

Formulated to be free of allergens derived from: Gluten, yeast, artificial colors and flavors. Do not consume this product if you are pregnant or nursing. Consult your physician for further information. As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used. Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.

Contraindications, Adverse or other Reactions:
Do not take if pregnant or nursing. Can be contraindicated in those with hypertension, liver or kidney disease.

DISCLAIMER: The information contained on this web site has not been evaluated by the FDA. It is not intended to treat, diagnose, cure or prevent any disease. Material on the Imupharm web site is provided for educational purposes only. Always seek the advice of your physician or other qualified health care provider with any questions you have regarding a medical condition, and before undertaking any diet, exercise or other health program.



Adaptogens
An adaptogen is a substance that nonspecifically increases the resistance of an organism and does not disturb normal biological parameters.

Rhodiola Rosea
Rhodiola rosea has been used as an adaptogenic herb in Russia and Scandinavia and traditional folk medicine to protect and stimulate the immune system. (Reference 1)

Schizandra Berry Extract
Schizandra with its adaptogenic properties has been recommended for centuries in China and Russia to balance endocrine hormones and the immune system.

Siberian Ginseng
Siberian ginseng is a plant that has been used to stimulate the immune system, improve general health, and enhance endurance. Siberian ginseng is regarded as an adaptogen. (Reference 2) Specific compounds of Siberian ginseng, known as eleutherosides, have been shown to be the primary compounds responsible for Siberian ginseng’s adaptogenic activity. (Reference 3)

Licorice Root
Licorice root is regarded as an adaptogen and has been used as immune booster for many health issues. Licorice contains two key components in adrenal health, glycyrrhetic acid and glycyrrhizin, which can activate the receptors for key adrenal hormones (mineralocorticoids and glucocorticoids). Glycyrrhetic acid also helps to keep mineralocorticoids and glucocorticoids in their more active forms.  Licorice also inhibits the enzyme that converts cortisol into the inactive cortisone. (Reference 4)

Pantothenic Acid
Pantothenic acid breaks down in the body to coenzyme A, which plays a large part in energy production. Coenzyme A is needed for function of the adrenal cortex. It also supports the adrenal glands in the making of key adrenal hormones that counteract the stress response. (Reference 5)

Vitamin Blend

Niacin plays a vital role in many metabolic functions in the body. It supplies energy to cells and assists in the production of adrenal hormones. (Reference 6)

Vitamin C levels are among the highest in the adrenal glands compared with other organs. It plays necessary roles in catecholamine and adrenal steroidogenesis synthesis, and for general health of the adrenals. (Reference 7)

The adrenal glands have low levels of B vitamins when our bodies are under stress. By supplementing with B vitamins, we replace what our adrenals have lost during stress.



(1) American Botanical Council. American Botanical Council.  rhodiola rosea: A Phytomedicinal Overview. http://www herbalgram org. 2002.

(2) American Botanical Council. American Botanical Council.  Eleuthero root. http://www herbalgram org. 2000.

(3) Cicero, A.F.; Derosa, G. et al. Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial. Arch Gerontol Geriatr Suppl. 2004;(9):69-73.

(4) Guilliams TG. Adrenal Stress:  Measureing and Treating. The Standard. 2000; 3(1).

(5) Slyshenkov, V.S.; Dymkowska, D.; and Wojtczak, L. Pantothenic acid and pantothenol increase biosynthesis of glutathione by boosting cell energetics. FEBS Lett. 2004; 569(1-3):169-172.

(6) AltHealth. Niacin:  Essential Background Reading. http://www althealth co uk. 2008.

(7) Patak, P.; Willenberg, H.S.; and Bornstein, S.R. Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla. Endocr Res. 2004; 30(4):871-875.